Advances and applications in single-cell and spatial genomics 2025-02-24
A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway 2025-02-24
Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A 2025-02-24
A deep learning framework for in silico screening of anticancer drugs at the single-cell level 2025-02-24
KPNA3 regulates histone locus body formation by modulating condensation and nuclear import of NPAT 2025-02-24
Integrative mapping of human CD8+ T cells in inflammation and cancer 2024-12-20
Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice 2024-12-20
Downregulating human leucocyte antigens on mesenchymal stromal cells by epigenetically repressing a β2-microglobulin super-enhancer 2024-12-20
A two-front nutrient supply environment fuels small intestinal physiology through differential regulation of nutrient absorption and host defense 2024-12-20
Two distinct regulatory pathways govern Cct2-Atg8 binding in the process of solid aggrephagy 2024-10-09
Gasdermin D-mediated metabolic crosstalk promotes tissue repair 2024-10-09
Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger 2024-10-09
“SWI/SNF chromatin-remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cells migration 2024-10-09
Structural Basis of Tethered Agonism and G protein coupling of Protease-Activated Receptor 2024-10-09
An inhibitory mechanism of AasS, an exogenous fatty acid scavenger: Implications for re-sensitization of FAS II antimicrobials 2024-10-09
Identification of BAF60b as a chromatin remodeling checkpoint of diet-induced fatty liver disease 2024-10-09
Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach 2024-08-29
Phase separation-competent FBL promotes early pre-rRNA processing and translation in acute myeloid leukaemia 2024-08-29
Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow targeted leukaemia drug delivery 2024-08-29
GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development 2024-08-07